Breaking News, Trials & Filings

ArGEN-X Antibody Hits Dose Escalation Goals

Will expand Ph Ib trial to hematology, solid tumor cohorts

By: Gil Roth

President, Pharma & Biopharma Outsourcing Association

ARGX-110, the lead antibody for arGEN-X, has met its translational development goals in the dose-escalation part of a Phase Ib study: all pre-specified biological activity measures –target engagement, effector functions, immune-modulation — were met, according to the company. The study also showed that ARGX-110 has a favorable safety profile and a dose has been selected to advance into the Phase Ib safety and efficacy expansion cohorts, which will start early in 2014 and are expected...

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